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We found that the glycolytic flux into the TCA cycle was reduced in Gclc fl/fl Mb1-Cre + FoB compared to Gclc fl/fl FoB, as indicated by increased M3-lactate and reduced M2-citrate (Supplementary Fig
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The processing model proposes that LYSET acts as a bridge between S1P and GNPTαβ to enhance the cleavage of the latter
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